New Publication

Nick, Paul and Colin contributed to the recently accepted paper “The Synthesis of Certain Derivatives and Analogues of (–)- and (+)-Galanthamine and an Assessment of their Capacities to Inhibit Acetylcholine Esterase” in The Journal of Organic Chemistry. This work, done in collaboration with the Banwell group at ANU, describes the syntheses of certain di- and mono-oxygenated derivatives and analogues of the alkaloid galanthamine. In contrast to results from docking studies, we show that none of these compounds strongly bind to acetylcholine esterase.



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